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The WinGX release contains three of the most powerful publically available programs for solving small molecule crystal structures, SIR92, SHELXS (both 86 and 97 versions) and DIRDIF. An interface to SIR97 is also provided. If none of these programs can solve your structure then you are in trouble.

All programs are quite automated. It should not be necessary to consult the help documents very often, but please read the notes on their implementation in WinGX. PATSEE is a Patterson interpretation program which may be useful if all others fail (DIRDIF has very powerful Patterson interpretation routines).